Felis ISSN 2398-2950

Cetrimide

Synonym(s): Centrimonium bromide

Contributor(s): Yolande Bishop, Rosanna Marsella

Introduction

Name

  • Cetrimide.

Class of drug

  • Antiseptic agent.

Description

Chemical name

  • Cetrimide is a mixture of tetradecyltrimethylammonium bromide with smaller amounts of dodecyltrimethylammonium bromide and cetrimonium bromide.
  • N,N,N-Trimethyl-1-hexadecanaminium bromide.
  • Hexadecyltrimethylammonium bromide.
  • Cetyltrimethylammonium bromide.

Molecular formula

  • C19, H42, BrN.

Molecular weight

  • 364.45.

Physical properties

  • Crystalline.

Uses

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Indications

  • Bacterial skin infections.
  • Cleansing of contaminated wounds.

Administration

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Precautions

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Further Reading

Publications

Refereed papers

  • Langford J Het al(1997)Clinical investigation of topical antimicrobials in healthy volunteers.Ann Pharmacother31(1), 34-38.
  • O'Brien T J (1993)Cetrimide necrosis.Australas J Dermatol34(3), 118.
  • Czarnecki Det al(1992)Prevention of post-excisional wound infections - a comparison of oral cephalexin with topical mupirocin and topical cetrimide-chlorhexidine cream.Int J Dermatol31(5), 359-360.
  • Galle H G & Venker-van Haagen A J (1986)Ototoxicity of the antiseptic combination chlorhexidine/cetrimide (Savlon) - effects on equilibrium and hearing.Vet Q8(1), 56-60.

Other sources of information

  • Tennant, B (1999)Small Animal Formulary.3rd edn. Cheltenham: British Small Animal Veterinary Association. ISBN: 0 9052 1452 8.

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