Felis ISSN 2398-2950

Cefoxitin

Contributor(s): Lauren Trepanier

Introduction

Name

  • Cefoxitin.

Class of drug

  • Cephamycin antibiotic.

Uses

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Indications

  • Treatment of abdominal sepsis such as peritonitis   Peritonitis  cause by Gram-negative bacteria.

Administration

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Pharmocokinetics

Precautions

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Interactions

with other drugs

Bacteriostatic agents
  • The bactericidal activity of cefoxitin may be affected by the concomitant use of bacteriostatic agents.

Loop diuretics

  • There may be an increased risk of nephrotoxicity if cefoxitin is used with amphotericin   Amphotericin B  or loop diuretics (eg furosemide   Furosemide  ); monitor renal function.
    Probenecid
  • Probenecid reduces the excretion of cefoxitin.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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