ISSN 2398-2950      

Amoxicillin

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Synonym(s): Amoxycillin


Introduction

Name

  • Amoxicillin.

Class of drug

  • Penicillin antibiotic.

Description

Chemical name

  • 6[D](-)-a-amino-p-hydroxyphenylacetamido] penicillanic acid.

Physical properties

  • Acid-stable, beta-lactamase-susceptible.

Uses

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Indications

  • Active against certain gram-positive and negative organisms.
  • Not active against those that produce penicillinases, eg someE. coli  Escherichia coli  andStaphylococcus aureus  Staphylococcus spp  .
  • The more difficult gram-negative organisms (Pseudomonas spp  Pseudomonas spp  andKlebsiella spp) are usually resistant.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

Probenecid

  • Will decrease the renal tubular secretion of penicillin antibiotics Penicillamine and thus prolong their blood levels.

Aminoglycosides

  • Do not mix in the same syringe as aminoglycosides.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. BSAVA, UK.
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