Felis ISSN 2398-2950

Amoxicillin

Synonym(s): Amoxycillin

Contributor(s): Lauren Trepanier

Introduction

Name

  • Amoxicillin.

Class of drug

  • Penicillin antibiotic.

Description

Chemical name

  • 6[D](-)-a-amino-p-hydroxyphenylacetamido] penicillanic acid.

Physical properties

  • Acid-stable, beta-lactamase-susceptible.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Active against certain gram-positive and negative organisms.
  • Not active against those that produce penicillinases, eg someE. coli  Escherichia coli  andStaphylococcus aureus  Staphylococcus spp  .
  • The more difficult gram-negative organisms (Pseudomonas spp  Pseudomonas spp  andKlebsiella spp) are usually resistant.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

Probenecid
  • Will decrease the renal tubular secretion of penicillin antibiotics   Penicillamine  and thus prolong their blood levels.

Aminoglycosides

  • Do not mix in the same syringe as aminoglycosides.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED