ISSN 2398-2950      

Acetazolamide

ffelis
Contributor(s):

Sheryl Krohne


Introduction

Name

  • Acetazolamide.

Class of drug

  • Carbonic anhydrase inhibitor.

Description

Chemical name

  • N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide.
  • 5-acetamido-1,3,4-thiadiazole-2-sulfonamide.

Molecular formula

  • C4H6N4O3S2.

Storage requirements

  • Store at room temperature.
  • After reconstitution: injection is stable for one week when refrigerated - use within 24 h without preservative.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Acetazolamide is a carbonic anhydrase inhibitor diuretic which is primarily used for the treatment of acute glaucoma   Glaucoma   and as long-term medical control of glaucoma in visual eyes.
  • It reduces the production of bicarbonate in aqueous humour and the water secreted with it, thus lowering intraocular pressure.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

  • Primidone   Primidone   absorption may be inhibited by oral acetazolamide.
  • Acetazolamide alkalinizes urine, thus the excretion rate of weak bases may be decreased, but weak acids increased.
  • Concomitant use of corticosteroids may exacerbate potassium depletion causing hypokalemia   Blood biochemistry: potassium  .

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Referred papers

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. BSAVA, UK.
  • Plumb D (1999) Veterinary Drug Handbook. 3rd Edn. Iowa State University Press.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!