Felis ISSN 2398-2950

Suspected adverse reactions to vaccination

Contributor(s): David Sutton

Introduction

  • Pet owners and veterinarians have begun to question the risk-benefit analysis of routine annual vaccination for adult pets particularly in the light of recent scares about adverse reactions to MMR vaccination in children, and increasing public awareness of potential health risks.
  • Individual veterinary surgeons retain ultimate responsibility for determining the vaccination schedule recommended to their clients.
  • There is no doubt that vaccines have been the key factor in the control of serious infectious diseases and have played an important part in the improvement of canine and feline health.
  • Owners pay to have their pet protected by vaccination - not to protect the general cat population.
  • When devising a vaccination policy for pets we need to base it on the worst responders so that we can give an assurance that all vaccinated pets are continually 100% protected.
  • The risk of infection in an individual is determined by many factors, including the level of infectious agent in the environment, as well as the individual's serological status.
  • An optimal vaccination strategy:
    • Maximizes the number of individuals within the population who receive vaccination.
    • Ensures that only individuals who have a realistic risk of contracting disease are vaccinated.
    • Minimizes the total number of vaccinations each individual receives in a lifetime.
      There is minimal benefit to be derived from vaccinating an individual with an antigen for which the likelihood of exposure is low and where clinical disease is, in any case, mild.

Risk analysis

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Adverse events

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Factors contributing to vaccine reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Séguin B (2002) Feline injection site sarcomas. Vet Clin North Am Small Anim Pract 32 (4), 983-995, viii PubMed.
  • Coyne M J, Burr J H, Yule T D et al (2001) Duration of immunity in cats after vaccination or naturally acquired infection. Vet Rec 149 (18), 545-548 PubMed.
  • Dodds W J (1999) More bumps on the vaccination road. Adv Vet Med 41, 715-732 PubMed.
  • Hustead D R, Carpenter T, Sawyer D C et al (1999) Vaccination issues of concern to practitioners. JAVMA 214 (7), 1000-1002 PubMed.
  • Ek-Kommonen C, Sihvonen L, Pekkanen K et al (1997) Outbreak of canine distemper in vaccinated dogs in Finland. Vet Rec 141 (15), 380-383 PubMed.
  • Kass P H, Barnes W G Jr., Spangler W L et al (1993) Epidemiological evidence for a causal relationship between vaccination and fibrosarcoma tumorigenesis in cats. JAVMA 203 (3), 396-405 PubMed.


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