Felis ISSN 2398-2950
Fluid therapy: for burns
Contributor(s): Claire Waters
- Severe burn → significant increase in vascular endothelium permeability throughout the body due to release of inflammatory mediators from burn site.
- Loss of plasma proteins from vascular space results in reduced plasma oncotic pressure and fluid shift from vascular space to interstitium.
- As much as 50% of plasma water may be lost from the circulation 2 hours after severe burn injury.
- Hyperkalemia may result from K+ release from damaged cells.
- Destruction of red blood cells occurs in the post-burn period because of increased fragility and morphological changes.
- Metabolic acidosis is common following severe burns.
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Other sources of information
- Saxon W D and Kirby R (1992)Treatment of acute burn injury and smoke inhalation.In: Kirk's Current Veterinary Therapy XI.Eds: R W Kirk and J D Bongura. Philadelphia: W B Saunders. pp 146-153. ISBN 0 7216 3293 9.