Felis ISSN 2398-2950

Dietetic diet: for liver insufficiency

Contributor(s): Marge Chandler

Pathophysiology

  • Hepatic lipidosis   Liver: lipidosis  , cholangitis   Liver: cholangitis  , neoplasia   Liver: primary hepatic neoplasia   and vascular anomalies comprise much of primary of  feline liver disease   Liver: chronic disease  .
  • The liver is also affected secondarily by many other diseases, eg pancreatitis   Pancreatitis  , inflammatory bowel disease   Inflammatory bowel disease: overview  , anemia   Anemia: overview   - termed reactive hepatitis.
  • The liver has over 1000 functions in metabolism and digestion which can be compromised with disease.
  • Impaired hepatic function and storage may result in malnutrition and vitamin and mineral deficiencies.
  • The goals of nutritional therapy are to help maintain the functions, decrease signs of hepatic encephalopathy   Hepatic encephalopathy   (HE), provide substrates (energy and protein) for hepatic repair, decrease oxidative damage and correct electrolyte disturbances.
  • Ammonia is converted to urea in the normal liver; where this is compromised in hepatopathies, ammonia increase, contributing to HE.

Dietary requirements

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Special considerations

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Diets

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Further Reading

Publications

Refereed papers
  • Recent references fromPubMed.
  • Bauer J E & Shenk P A (1989)Nutritional management of hepatic disease. Vet Clin North Am Small Anim Pract19(3), 513-526.

Other sources of information

  • Marks S L (2012)Nutritional management of hepatobiliary disease.In: Applied Veterinary Clinical Nutrition.Editors Fascetti AJ and Delaney SJ. Wiley Blackwell, West Sussex, U.K. pp 235-250.
  • Meyer H, Twedt D C, Roudebush P, Dill-Macky E (2010)Hepatobiliary Disease.In: Small Animal Clinical Nutrition 5th Edition. Editors Hand MS, Thatcher CD, Remillard RL, Roudebush P, Novotny BJ. Mark Morris Institute, Topeka, Kansas. pp 1155-1194.


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