ISSN 2398-2950      

Skin: panniculitis

ffelis
Contributor(s):

David Godfrey

Synonym(s): Nodular panniculitis, necrotizing steatitis


Introduction

  • Cause: inflammation of subcutaneous fat.
  • Signs: sinus tracts, nodules and fistulae.
  • Diagnosis: history, signs, histopathology.
  • Treatment: surgery, antibiosis, immunosuppressive glucocorticoids, Vitamin E.
  • Prognosis: varies according to cause.

Pathogenesis

Etiology

Nutritional

  • Relative or absolute vitamin E deficiency (due to diet rich in oily fish, eg tuna).

Predisposing factors

General

  • May develop after subcutaneous injection.

Pathophysiology

  • Inflammation of subcutaneous fat.
  • Damage to fat cells releases lipid into extracellular space.
  • Lipid is converted to fatty acids and these are potent inflammation inducers.
  • Granulomatous reactions to fatty acids develop.
  • Can be sterile or infectious.

Timecourse

  • Weeks.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Alander-Damsten Y K, Brander E E & Paulin L G (2003) Panniculitis, due to Mycobacterium smegmatis, in two Finnish cats. J Feline Med Surg (1), 19-26 PubMed.
  • Scott D W & Anderson W I (1988) Panniculitis in dogs and cats - a retrospective study of 78 cases. JAAHA 24 (5), 551-9 VetMedResource.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code