Felis ISSN 2398-2950

Meningomyelitis: bacterial and fungal

Contributor(s): Laurent Garosi, David Godfrey

Introduction

  • Cause: infection with bacteria or fungi.
  • Signs: spinal pain, depression, intermittent pyrexia, neurological deficits.
  • Diagnosis: CSF cytology, identification of etiological agent.
  • Treatment: appropriate antimicrobial therapy and supportive care.
  • Prognosis: guarded.

Pathogenesis

Etiology

Bacterial

Fungal

Predisposing factors

General

  • Bite wound.
  • Migration of foreign body, eg grass awn.
  • Spinal surgery.
  • Extension of infection from diskospondylitis Diskospondylitis.

Pathophysiology

  • Variety of organisms may be involved, the most common being Staphylococcus spp.
  • Infection may be generalized or localized.
  • Meningitis may be seen in association with spinal cord infection myelitis or encephalitis.
  • Focal infection may   →   space occupying lesion, eg empyema    →   spinal cord compression   →   focal neurological signs.
  • Abscessation of spinal cord may develop   →   intramedullary mass.

Timecourse

  • Some cases progress acutely over hours.
  • Chronic deterioration over days to weeks particularly with focal lesions.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Kline K L, Joseph R J, Averill D R (1994) Feline infectious peritonitis with neurologic involvement - clinical and pathological findings in 24 cats. JAAHA 30 (2), 111-118 VetMedResource.
  • Sorjonen D C (1992) Myelitis and meningitis. Vet Clin North Am 22 (4), 951-964 PubMed.

Other sources of information

  • Kent M (2006) Bacterial infections of the central nervous system. In: Greene CE (ed) Infectious diseases of the dog and cat. 3rd edn. St Louis: Saunders Elsevier, pp 754-775.
  • Malik R, Krockenberger M, O'Brien C R et al(2006) Crytococcosis. In: Greene C E (ed) Infectious diseases of the dog and cat.3 rd edn. St Louis: Saunders Elsevier, pp 584-598.


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