Felis ISSN 2398-2950

Lymphocytic / plasmacytic enteritis

Synonym(s): Inflammatory bowel disease, IBD

Contributor(s): Ed Hall, Philip K Nicholls, Kenneth Simpson

Introduction

  • An idiopathic chronic inflammatory disease of small and/or large intestine Inflammatory bowel disease: overview.
  • Cause: unknown; immune-mediated sensitivity to range of possible antigens, eg diet, parasite, bacteria etc.
  • Signs: vomiting, diarrhea and weight loss.
  • Diagnosis: intestinal biopsy and histopathology, (infiltration of lamina propria by lymphocytes and plasmacytes).
  • Treatment: diet and immunosuppression.

Pathogenesis

Etiology

Pathophysiology

  • Hypothesized hypersensitivity to antigen(s)   →   chronic inflammation   →   loss of mucosal integrity and increased permeability   →   antigens can access lamina propria   →   further immune reaction and inflammation   →   malabsorption   →   protein-losing enteropathy.
  • May be a non-specific reaction to a variety of agents.

Timecourse

  • Chronic.

Diagnosis

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Guilford W G, Jones B R, Markwell P J et al (2001) Food sensitivity in cats with chronic idiopathic gastrointestinal problems. JVIM 15 (1), 7-13 PubMed.
  • Simpson K W, Fyfe J, Cornetta A et al (2001) Subnormal concentrations of serum cobalamin (vitamin B12) in cats with gastrointestinal disease. JVIM 15 (1), 26-32 PubMed.
  • Weiss D J, Gagne J M & Armstrong P J (1996) Relationship between inflammatory hepatic disease and inflammatory bowel disease, pancreatitis, and nephritis in cats. JAVMA 209 (6), 1114-1116 PubMed.
  • Yamasaki K, Suematsu H, Takahashi T (1996) Comparison of gastric and duodenal lesions in dogs and cats with and without lymphocytic-plasmacytic enteritis. JAVMA 209 (1), 95-97 PubMed.
  • Edwards D F, Russell R G (1987) Probable vitamin K-deficient bleeding in two cats with malabsorption syndrome secondary to lymphocytic-plasmacytic enteritis. J Vet Intern Med (3), 97-101 PubMed.
  • Willard M D, Dalley J B, Trapp A L (1985) Lymphocytic-plasmacytic enteritis in a cat. JAVMA 186 (2), 181-182 PubMed.


ADDED