ISSN 2398-2950      

Hypertrophic osteopathy

ffelis

Synonym(s): Marie's disease


Introduction

  • Rare in cat.
  • A secondary change indicating another disease process, eg lung tumors (most often), other thoracic conditions, esophageal tumor, adenocarcinoma of liver/prostate, embryonal rhabdomyosarcoma of bladder.
  • Cause: increased peripheral blood flow and deposition of new periosteal bone along long bone diaphyses (especially extremities).
  • Signs: enlargement of distal extremities, swollen and warm limbs, lameness.
  • Treatment: treatment of underlying causal condition +/- glucocorticoids +/- analgesia.
  • Prognosis: guarded to poor - dependent on successful treatment of primary disease process.

Pathogenesis

Etiology

  • Speculative.

Specific

Pathophysiology

  • Proliferation of new periosteal bone secondary to another disease process.
  • Periosteal proliferation often begins with digits and can extend as far proximally as the femur or humerus.
  • Various theories (neurovascular mechanism).

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

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