Felis ISSN 2398-2950

Injection-site associated sarcoma

Synonym(s): Post-vaccinational sarcoma

Contributor(s):

Introduction

  • First reported early 1990's Suspected adverse reactions to vaccination.
  • Low incidence (relative to number of vaccinations performed).
  • Cause: tumor develops at site used for injection, most often vaccination (microchip implantation or injection of diverse drugs have also been reported as a cause).
  • Signs: firm soft tissue swelling usually between scapules, locally aggressive.
  • Diagnosis: histopathology.
  • Treatment: surgical excision with wide margins. Adjuvant radiation therapy or chemotherapy may be indicated in some cases.
  • Prognosis: guarded.
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Pathogenesis

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Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

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