Felis ISSN 2398-2950

Esophagus: neoplasia

Contributor(s): Philip K Nicholls, Marion O'Leary

Introduction

  • Very rare. Less than 0.5% of all alimentary neoplasms.
  • Cause: benign papillomas not documented in the cat. Primary tumours include squamous cell carcinoma, less commonly adenocarcinoma, or adenosquamous carcinoma, fibrosarcoma, neuroendocrine carcinoma. Occasionally lymphoma, or metastasis/local invasion from thyroid carcinoma or tracheobronchial carcinoma.
  • Signs: regurgitation.
  • Diagnosis: radiography, endoscopy, biopsy.
  • Treatment: surgical resection (rarely).

Pathogenesis

Predisposing factors

General

  • Regurgitation.

Pathophysiology

  • Metastatic neoplasia:
    • Thyroid.
    • Pulmonary.
  • Primary neoplasia:
    • Squamous cell carcinoma - most common esophageal tumor in the cat. Some studies report more males than females affected, and castrated males over-represented.
    • Squamous cell carcinoma may metastasize to tracheobronchial and mediastinal lymph nodes, also caudal cervical nodes, lungs, kidneys and spleen.
    • Leiomyosarcoma possible also, but not well-documented.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Gualtieri M (2001) Esophagoscopy. Vet Clin North Am Small Anim Pract 31 (4), 605-630 PubMed.
  • Shinozuka J, Nakayama H, Suzuki M et al (2001) Esophageal adenosquamous carcinoma in a cat. J Vet Med Sci 63 (1), 91-93 PubMed.
  • Gualteri M, Monzeglio M G, Di Giancamillo M (1999) Oesophageal squamous cell carcinoma in two cats. J Small Anim Pract 40 (2), 79-83 PubMed.
  • Patnaik A K, Erlandson R A, Lieberman P H (1990) Esophageal neuroendocrine carcinoma in a cat. Vet Pathol 27 (2), 128-130 PubMed.

Other sources of information

  • Head K W, Else R W & Dubielzig R R (2002) "Tumors of the alimentary tract" In: Meuten DJ (Ed.) Tumors in Domestic Animals. 4th Edn. Iowa State Press.


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