ISSN 2398-2950      

Arthritis: polyarthritis - idiopathic

ffelis
Contributor(s):

Introduction

  • Inflammatory, non-erosive, polyarthritis.
  • Cats which have been diagnosed with this condition have failed to satisfy the criteria for rheumatoid arthrtitis, SLE, and periosteal proliferative polyarthritis.
  • Other body systems may be involved; categorized (into 4) according to concomitant pathology.
  • Signs: complications, eg dermatitis, glomerulonephritis Glomerulonephritis, uveitis Uveitis: viral, retinitis.
  • Diagnosis: radiography, cytopathology.
  • Treatment: depends on etiology.
  • Prognosis: fair.

Pathogenesis

Etiology

  • A definite cause and effect relationship between the polysynovitis and the concomitant pathology has yet to be confirmed.

Pathophysiology

See immune mediated arthritides

  • Categories of the disease are classified by association with concomitant pathology. It is thought that co-existing pathology contributes to immune complex formation and thus leads to Type 3 (immune complex) hypersensitivity in the synovial membrane.

Type 1

  • The etiopathogenesis may be similar in all cases, but individual susceptibilities dictate which cats develop progressive disease.

Type 2

  • The chronic infection is thought to act as an antigen source for persistent immune complex formation.

Type 3

  • It is thought that the gastrointestinal disease leads to an increase in intestinal permeability to foreign antigens, resulting in chronic formation of immune complexes.

Type 4

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code