Felis ISSN 2398-2950

Acute metritis

Synonym(s): Post-partum metritis

Contributor(s): Prof Gary England, Rob Lofstedt, Mushtaq Memon

Introduction

  • Usually develops within 1 week of parturition (also abortion or mating).
  • Cause: uterine contamination with bacteria, no underlying endocrine change (unlike pyometra Pyometra).
  • Signs: vaginal discharge: sanguinous to purulent. Pyrexia, anorexia, depression, tenesmus and agalactia.
  • Treatment: broad-spectrum antibiotics, supportive, follow-up hysterectomy.
  • Prognosis: guarded depending on condition of queen. Potentially fatal if uterus ruptures.

Pathogenesis

Etiology

Predisposing factors

General

Specific

Pathophysiology

  • Escherichia coli Escherichia coli.
  • Proteus spp.
  • Staphylococcus spp Staphylococcus spp.
  • Streptococcus spp Streptococcus spp.
  • Other gram-negative and gram-positive vaginal commensals.
  • Vaginal commensals   →   uterus   →   proliferate in lochia   →   endotoxin release   →   :
    • Interference with ADH (see pyometra complex)   →   dehydration, uremia Uremia.
    • Pathogen chemotaxis   →   neutrophilia   →   pooling of neutrophils in uterus   →   left-shift leukogram.

Timecourse

  • Usually within 1 week of parturition (or other predisposing event).

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dubey J P, Lindsay D S (1989) Transplacental Neospora caninum infection in cats. J Parasitol 75 (5), 765-771 PubMed.
  • Henderson R T (1984) Prostaglandin therapeutics in the bitch and queen. Aust Vet J 61 (10), 317-319 PubMed.
  • Burke T J (1982) Prostaglandin F2 alpha in the treatment of pyometra-metritis. Vet Clin North Am Small Anim Pract 12 (1), 107-109 PubMed.


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