Exotis ISSN 2398-2985

Reptiles

Yohimbine

Synonym(s): Yohimbine HCl, Antagonil, Yobine

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Yohimbine.

Class of drug

  • Indolealkylamine alkaloid.
  • Alpha-2 adrenergic antagonist.

Description

Chemical name

  • Yohimbine HCl: Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, hydrochloride (1:1), (16.alpha.,17.alpha.)-.

Molecular formula

  • C21H26N2O3.

Molecular weight

  • 390.9 (yohimbine HCl).

Storage requirements

  • Store at room temperature.
  • Keep out of light.

Uses

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Indications

  • To reverse effects of xylazine Xylazine.
  • It may also be used to reverse toxic effects of amitraz.
  • It may also be used to reverse effects of medetomidine Medetomidine and dexmedetomidine, but atipamezole Atipamezole more commonly used in these situations.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Mader D R (2006) Ed Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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