Exotis ISSN 2398-2985

Reptiles

Praziquantel

Synonym(s): Droncit, Drontal (praziquantel + febantel + pyrantel), Profender (praziquantel + emodepside), Milbemax (praziquantel + milbemycin)

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Praziquantel.

Class of drug

  • Prazinoisoquinolone derivative.
  • Broad-spectrum anthelmintic.

Description

Chemical name

  • 2-cyclohexycarbonyl-[1,2,3,6, 7, lib]-hexahydro-4H-pyrazino [2,1-a] isoquinoline-4-one.

Molecular formula

  • C19H24N2O2.

Molecular weight

  • 312.41.

Physical properties

  • White to practically white, hygroscopic, bitter tasting, crystalline powder, either odorless or having a faint odor.
  • Insoluble in water and relatively soluble in alcohol.

Storage requirements

  • Store at room temperature, in tight containers and protected from light.

Uses

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Indications

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Watson M (2009) Praziquantel. J Exotic Pet Med 18 (3), 229-231 ExoticPetMed.
  • Schilliger L, Betremieux O, Rochet J et al (2009) Absorption and efficacy of a spot-on combination containing emodepside plus praziquantel in reptiles. Revue de Medecine Veterinaire 160 (12), 557-561 VetMedResource.

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Saunders, USA.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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