Exotis ISSN 2398-2985

Reptiles

Oxfendazole

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Oxfendazole.

Class of drug

  • Benzimidazole anthelmintic.

Description

Chemical name

  • 5-(phenylsulfinyl)-1H-benzimidazol-2-ylcarbamic acid methyl ester.

Molecular formula

  • C15H13N3O3S.

Molecular weight

  • 315.3.

Physical properties

  • White or almost white powder possessing a characteristic odor.
  • It is practically insoluble in water.

Storage requirements

  • Store in a dry environment at room temperature.

Uses

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Indications

  • Infestations with ascarids, oxyurids, lungworms, other nematodes and some cestodes.
  • Faster effect than fenbendazole (12 days vs 31 days in tortoises).

Administration

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Pharmacokinetics

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Manire C A, Kinsel M J, Anderson E T et al (2008) Lungworm infection in three loggerhead sea turtles, Caretta caretta. J Zoo Wildl Med 39 (1), 92-98.
  • Giannetto S, Brianti E, Poglayen G et al (2007) Efficacy of oxfendazole and fenbendazole against tortoise (Testudo hermanni) oxyurids. Parasitol Res 100 (5), 1069-1073.

Other sources of information

  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
  • McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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