Exotis ISSN 2398-2985

Reptiles

Levamisole

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Levamisole.

Class of drug

  • Imidazothiazole anthelmintic.
  • Immunostimulant.

Description

Chemical name

  • (S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole.

Molecular formula

  • C11H12N2S.

Molecular weight

  • 204.29.

Physical properties

  • Levamisole HCL occurs as a white to pale cream colored, odorless or nearly odorless, crystalline powder.

Storage requirements

  • Store at room temperature (15-30°C/59-86°F).
  • Levamisole phosphate injection should be store at temperatures <21°C/69.8°F.
  • Freezing should be avoided.
  • Protect from light.

Uses

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Indications

  • Indicated for the treatment of nematodes, particularly when oral administration of drugs is not possible (most commonly in shy chelonians).
  • May be used for lungworms, particularly in snakes.
  • Immunocompromise.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Neostigmine or organophosphates
  • Levamisole's toxic effects may be enhanced by Neostigmine or organophosphate exposure.
  • Avoid concurrent administration of chloramphenicol.

With diagnostic tests

  • Text here

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Elsevier Saunders. USA. pp 564.
  • McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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