Exotis ISSN 2398-2985

Reptiles

Gallamine triethiodide

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Gallamine triethiodide.

Class of drug

  • Non-depolarizing muscle relaxant, modifier of neuromuscular transmission.

Description

Chemical name

  • 2-[2,3-bis[2-(triethylazaniumyl)ethoxy]phenoxy]ethyl-triethylazanium;triiodide.

Molecular formula

  • C30H60N3O3+3 · 3 I− (gallamine triethiodide).
  • C24H45N3O3 (gallamine).

Molecular weight

  • 891.53 (gallamine triethiodide).
  • 423.63 (gallamine).

Physical properties

  • Odorless, white amorphous powder.
  • Freely soluble in water and alcohol.

Storage requirements

  • Store at room temperature.
  • Protect from light and freezing.

Uses

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Indications

  • Used for immobilization and transport of crocodiles.
  • Historically, it has been used for capture and transportation of wild African crocodiles.
  • Auditory, visual and tactile stimulation must be minimal, as the animal will be fully conscious.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Aminoglycosides, clindamycin, lincomycin, magnesium salts, polymyxin B sulfate - enhanced neuromuscular blockade.
  • Quinidine - enhanced neuromuscular blockade.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Morgandavies A M (1980) Immobilization of the Nile crocodile (Crocodilus niloticus) with gallamine triethiodide. J Zoo Wildl Med 11 (3), 85-87 VetMedResource.

Other sources of information

  • Fleming G J (2014) Crocodiles (Crocodiles, Alligators, Caima, Gharial). In: Zoo Animal and Wildlife Immobilization and Anesthesia. 2nd edn. Eds: West G, Heard D & Caulkett N. Wiley-Blackwell, USA. pp 325-336.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Saunders, USA.
  • Bishop Y (1998) Ed The Veterinary Formulary. British Veterinary Association and Royal Pharmaceutical Society, UK.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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