Exotis ISSN 2398-2985

Reptiles

Flunixin

Synonym(s): Banamine, Equileve, Flunixamine, Flumeglumine, Compamine

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Flunixin.

Class of drug

  • Non-steroidal anti-inflammatory drug (NSAID).

Description

Chemical name

  • 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid.

Molecular formula

  • C14H11F3N2O2.C7H17NO5.

Molecular weight

  • 296.24.

Physical properties

  • White to off-white powder soluble in water and alcohol.

Storage requirements

  • Between 2-30°C/35.6-86°F.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Flunixin controls moderate to severe visceral and somatic pain.
  • To minimize the effects of endotoxemia; pre-treatment is most effective, as slow onset of action.
  • The use of flunixin meglumine is not common in reptiles and is declining in small animal medicine since the introduction of other NSAIDs with higher therapeutic indexes.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • Do not administer with anticoagulants, other anti-inflammatory agents, sulfonamides and phenytoin.
Fluoroquinolones
  • In man there is an increased risk of convulsions if NSAIDs are administered with fluoroquinolones.
Anti-hypertensive agents
  • NSAIDs may antagonize the hypotensive effects of anti-hypertensives, eg beta-blockers.
Diuretics
  • The concomitant use of diuretics may increase the risk of nephrotoxicity.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Saunders, USA.
  • McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

ADDED