Exotis ISSN 2398-2985

Reptiles

Fipronil

Synonym(s): Frotline

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Fipronil.

Class of drug

  • Phenylpyrazole antiparasitic agent.

Description

Chemical name

  • 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile.

Molecular formula

  • C12H4Cl2F6N4OS.

Molecular weight

  • 437.14.

Physical properties

  • White powder.

Storage requirements

  • Store in a cool, dry area, away from food and feedstuffs.

Uses

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Indications

  • Treatment and control of mites and ticks in reptiles [Acariasis].

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • A low dose of amitraz has been shown to have a synergistic effect on the speed of tick kill.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Farmaki R, Simou C, Papadopoulos E et al (2013) Effectiveness of a single application of 0.25% fipronil solution for the treatment of hirstiellosis in captive green iguanas (Iguana iguana): an open-label study. Parasitol 140 (9), 1144-1148 PubMed.
  • Burridge M J, Peter T F, Allan S A et al (2002) Evaluation of safety and efficacy of acaricides for control of the African tortoise tick (Amblyomma marmoreum) on leopard tortoises (Geochelone pardalis). J Zoo Wildl Med  33 (1), 52-57 PubMed.

Other sources of information

  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Saunders, USA.
  • Mader D R (2006) Ed Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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