Exotis ISSN 2398-2985

Reptiles

Calcium gluconate

Synonym(s): Calcium salts

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Calcium gluconate.

Class of drug

  • Mineral.

Description

Chemical name

  • D-gluconic acid calcium salt (2:1).

Molecular formula

  • C12H22CaO14.

Molecular weight

  • 430.06.

Physical properties

  • Sparingly soluble in water.

Storage requirements

  • Room temperature.
  • Injectable calcium gluconate should not be frozen.

Uses

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Indications

  • To treat conditions arising from calcium deficiency.
  • Hypocalcemic tetany Tetany: lizard.
  • Uterine inertia .
  • Management of hyperkalemic cardiotoxicity associated with urinary obstruction.
  • Calcium gluconate rapidly corrects arrhythmias but has a short duration of effect (5-10 min).

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Do not add calcium salts to IV solutions containing bicarbonate, carbonate, phosphate, sulfate or tartrate salts.
  • Arrythmias may develop if IV calcium is given to patients on digoxin therapy.
  • Antagonizes the effects of verapamil.
  • Calcium gluconate cannot be used with metoclopramide [Metoclopramide].
  • Cannot be used with propofol [Propofol], amphotericin B [Amphotericin B] and methylprednisolone [Methylprednisolone].
  • Concurrent use with thiazide diuretics may facilitate hypercalcemia.
  • Oral administration can reduce the amount of tetracyclines absorbed from the GI tract.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK.
  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Elsevier Saunders, USA. pp 564.
  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • Veterinary Medicines Directorate (2013) Veterinary Medicines Guidance Notes. Website: www.gov.uk.
  • Mader D R (2006) Ed Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.
  • McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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