Exotis ISSN 2398-2985

Reptiles

Bupivacaine

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Bupivacaine.

Class of drug

  • Local anesthetic.

Description

Chemical name

  • 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide.

Molecular formula

  • C18H28N2O.

Molecular weight

  • 288.435 g/mol.

Physical properties

  • Clear, sterile solution.

Storage requirements

  • <25°C/77°F.

Uses

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Indications

  • Used predominantly as a local anesthetic Anesthesia overview.
  • It can also be used as an intra-articular injection to relief articular pain.
  • Has a longer duration of action than most other local anesthetic agents.
  • Effects not seen for up to 30 min but usually within 15-20 min.
  • Duration of action 4-7 h in most rodents.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Propranolol.
  • May increase bupivicaine effects if administered concurrently.
Other local anesthetics
  • Dose of bupivacaine should be reduced when used in combination with other local anesthetics.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Mans C (2014) Intrathecal drug administration in turtles and tortoises. J Exotic Pet Med 23 (1), 67-70 VetMedResource.

Other sources of information

  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Ramsey I et al (2011) Bupivacaine. In: BSAVA Small Animal Formulary. 7th edn. BSAVA, UK.
  • Mader D R (2006) Ed Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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