Exotis ISSN 2398-2985

Reptiles

Atipamezole

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Atipamezole.

Class of drug

  • Selective alpha-2 adrenoreceptor antagonist.

Description

Chemical name

  • 4-2(-ethyl-1,3-dihydroinden-2-yl)-3H imidazole.

Molecular formula

  • C14H16N2.

Molecular weight

  • 212.29.

Physical properties

  • The injection is a clear, colorless solution.

Storage requirements

  • The injection should be stored at room temperature and protected from light.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Reversal of sedative effects of medetomidine and dexmedetomidine.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Doss G A, Fink D M, Sladky K K et al (2017) Comparison of subcutaneous dexmedetomidine-midazolam versus alfaxalone-midazolam sedation in leopard geckos (Eublepharis macularius). Vet Anaesth Analg 44 (5), 1175-1183 PubMed.
  • Hansen L L & Bertelsen M F (2013) Assessment of the effects of intramuscular administration of alfaxalone with and without medetomidine in Horsfield’s tortoises (Agrionemys horsfieldii). Vet Anaesth Analg 40 (6), e68-E75 PubMed.
  • Olsson A & Phalen D (2013) The effects of decreased body temperature on the onset, duration and action of medetomidine and its antagonist atipamezole in juvenile farmed estuarine crocodiles (Crocodylus porosus). Vet Anaesth Analg 40 (3), 272-279 PubMed.

Other sources of information

  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Blackwell Publishing, USA. pp 1296.
  • Ramsey I (2014) BSAVA Small Animal Formulary. 8th edn. BSAVA, UK. ISBN: 9781905319657.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Elsevier Saunders, USA. pp 564.
  • Veterinary Medicines Directorate (2013) Veterinary Medicines Guidance Notes. Website: www.gov.uk.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

ADDED