ISSN 2398-2985      

Sodium bicarbonate

6guinea pig

Synonym(s): Baking soda


Introduction

Name

  • Sodium bicarbonate.

Class of drug

  • Electrolyte and alkalinizing agent.

Description

Chemical name

  • Sodium bicarbonate.

Molecular formula

  • NaHCO3.

Molecular weight

  • 84.

Physical properties

  • White, crystalline powder having a slightly saline or alkaline taste.
  • Soluble in water and insoluble in alcohol.

Storage requirements

  • Tablets: tight containers at room temperature.
  • Sodium bicarbonate injection: room temperature and avoid freezing.
  • Sodium bicarbonate powder is stable in dry air, but will slowly decompose upon exposure to moist air.

Uses

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Indications

  • Treatment of metabolic acidosis. Active correction of acid-base imbalance requires blood gas analysis.
  • Adjunctive therapy in the treatment of hypercalcemic or hyperkalemic crises.
  • Unlikely to be effective to alkalinize urine in guinea pigs, particularly when given orally.

Administration

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Precautions

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Interactions

with other drugs

  • Do not give orally within 1-2 h of giving other drugs.
Phenobarbitone
  • Increases the excretion of phenobarbitone.
Tetracyclines, especially doxycycline
  • Increases the excretion of tetracyclines.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.
  • Bishop Y (1998) The Veterinary Formulary. 4th edn. British Veterinary Association and Royal Pharmaceutical Society.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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