Exotis ISSN 2398-2985

Guinea Pigs

Loperamide

Synonym(s): Loperamide hydrochloride, Diareze, Imodium, Norimode

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Loperamide.

Class of drug

  • Opiate (derivative).

Description

Chemical name

  • 4-(4-chlorophyenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide.
  • 4-(p-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide.

Molecular formula

  • C29H33ClN2O2.

Molecular weight

  • 477.03.

Physical properties

  • Capsules.
  • Syrup.

Storage requirements

  • Store at room temperature.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Non-specific acute and chronic diarrhea.
  • Irritable bowel syndrome.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • Do not give with ketoconazole or itraconazole.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, United Kingdom. pp 338.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

ADDED