Exotis ISSN 2398-2985

Guinea Pigs

Ketoprofen

Synonym(s): Ketofen, Orudis, Oruvail

Contributor(s): Vetstream Ltd, David Perpinan

Introduction

Name

  • Ketoprofen.

Class of drug

  • Propionic acid, non-steroidal anti-inflammatory drug (NSAID).

Description

Molecular formula

  • C16H14O3.

Molecular weight

  • 254.28.

Physical properties

  • Off white to white, fine to granular powder.
  • Practically insoluble in water, but freely soluble in alcohol.

Storage requirements

  • Oral form: room temperature in tight, light resistant containers.
  • Injectable form: room temperature.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • To control mild to moderate pain.
  • Not recommended for pre-operative administration.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

NSAIDs
  • Do not administer concurrently.
  • Increased risk of GI ulceration.
  • Increased risk of convulsions (man).
Diuretics
  • Increased risk of nephrotoxicity.
Anti-hypertensive agents
  • NSAIDs may antagonize the hypotensive effects of anti-hypertensives, eg beta-blockers.
Anti-coagulants
  • Do not administer concurrently.
Other substances
  • Do not mix with other substances in the same syringe.

with diagnostic tests

  • May falsely elevate glucose and bilirubin.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, United Kingdom. pp 338.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley Blackwell. pp 1296.
  • Ramsey I (2014) BSAVA Small Animal Formulary. 8th edn. BSAVA. ISBN: 9781905319657.
  • Veterinary Medicines Directorate (2013) Veterinary Medicines Guidance Notes. Website: www.gov.uk.
  • Hawk C T & Leary S (1995) Formulary for Laboratory Animals. 2nd edn. Compiled by in association with ACLAM. Iowa State University Press, Ames.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

ADDED