ISSN 2398-2985      

Hematology: leukocyte (WBC)

4ferrets

Synonym(s): WBC


Overview

  • The term leukocyte includes all white blood cells (neutrophils, eosinophils, basophils, monocytes, lymphocytes) and their precursors.
  • Leukocytes protect the body against foreign substances by phagocytosis and antibody production:
    • Granulocytes (neutrophils, eosinophils, basophils ) and monocytes are all phagocytic cells.
    • Lymphocytes produce antibodies (B cells), or are concerned with cell-mediated immunity (T cells).
  • Lymphocytes and neutrophils are the predominant white blood cells in ferrets.

Sampling

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Tests

Methodologies

  • Manual hemocytometer: accuracy +/- 20%; not commonly used in ferrets.
  • Electronic counting systems: accuracy +/- 3-5%.
  • QBC-V hematology system.
  • Automated differentials provide useful information but are not an alternative to blood smear evaluation.

Availability

  • All commercial laboratories and selected practices.

Validity

Sensitivity

  • Sensitive.

Specificity

  • Non-specific.

Predictive value

  • Useful if used in conjunction with differential white blood cell counts and other diagnostic techniques.

Technique (intrinsic) limitations

  • Leukocyte counts cannot provide a specific diagnosis in isolation.

Technician (extrinsic) limitations

  • Repeatability.
  • Level of skill.

Result Data

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • Campbell T W & Ellis C K (2007) Avian and Exotic Hematology and Cytology. 3rd edn. Wiley-Blackwell. ISBN: 978-0813818115.
  • Feldman B F, Zinkl  J G & Jain N C (eds) (2000) Schalm's Veterinary Hematology. 5th edn. Lippincott, Williams & Wilkins, USA.
  • Fudge A M (1999) Laboratory Medicine. Avian and Exotic Pets. W B Saunders Co. ISBN: 0721 676 790.

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