Exotis ISSN 2398-2985

Ferrets

Hematology: basophil

Contributor(s): Vetstream Ltd, David Perpinan

Overview

  • Granular leukocyte with a lobed, pale-staining nucleus and a cytoplasm containing typical basophilic cytoplasmic granules.
  • Basophils promote inflammatory and allergic (immediate and delayed hypersensitivity) reactions by release of mediators such as histamine, heparin, serotonin and hyaluronic acid.
  • References of basophilia in ferrets have not been found in the scientific literature, so abnormal basophil counts are believed to be rare or very rare in ferrets.
  • Basophils are difficult to distinguish from circulating mast cells. Mast cells are rarely seen in ferrets but could appear in mast cell tumors.

Sampling

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Tests

Validity

Sensitivity

  • It seems basophilia is rare in ferrets and therefore it may not be a sensitive test to detect any condition.

Specificity

  • Basophilia, if presented, may be specific of allergic reactions or some type of tumors.

Result Data

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Hein J, Spreyer F, Sauter-Louis C et al (2012) Reference ranges for laboratory parameters in ferrets. Vet Rec171, 218 PubMed.

Other sources of information

  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • Campbell T W & Ellis C K (2007) Avian and Exotic Hematology and Cytology. 3rd edn. Wiley-Blackwell. ISBN: 978-0813818115.


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