ISSN 2398-2985      

Selamectin

4ferrets

Synonym(s): Revolution


Introduction

Name

  • Selamectin.

Class of drug

  • Avermectin parasiticide.

Description

Chemical name

  • (5Z,25S)-25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-5-demethoxy-25-de(2-methylpropyl)-22,23-dihydro-5-hydroxyiminoavermectin A1a.

Molecular formula

  • C43H63NO11.

Molecular weight

  • 770.0.

Physical properties

  • White powder.

Storage requirements

  • Store in the unopened foil package in a dry place.
  • Do not store above 30°C/86°F.
  • Highly flammable: keep away from heat, sparks, open flames or other sources of ignition.

Uses

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Indications

Can be used in ivermectin-sensitive animals.
  • Treatment of ectoparasites and some endoparasites, mainly ear mites, fleas and heartworm in ferrets.

Administration

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Pharmacokinetics

Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Fox-Alvarez W A, Moreno A R & Bush J (2015) Diagnosis and successful surgical removal of an aural ceruminous gland adenocarcinoma in a domestic ferrets (Mustela putorius furo). J Exotic Pet Med 24 (3), 350-355 VetMedResource.
  • Fisher M, Beck W & Hutchinson M J (2007) Efficacy and Safety of Selamectin (Stronghold®/Revolution™) Used Off-Label in Exotic Pets. Int J Appl Res Vet Med 5 (3), 87-96 JARVM.
  • Miller D S, Eagle R P, Zabel S et al (2006) Efficacy and safety of selamectin in the treatment of Otodectes cynotis infestation in domestic ferrets. Vet Rec 159 (22), 748 VetMedResource.

Other sources of information

  • Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 195.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
  • Quesenberry K E & Carpenter J W (2004) Formulary. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 2nd edn. pp 436-444.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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