ISSN 2398-2985      

Hemoglobin glutamer

4ferrets

Synonym(s): Oxyglobin


Introduction

Name

  • Haemoglobin glutamer-200 (bovine).

Class of drug

  • Blood substitute.
  • An ultrapurified, polymerized hemoglobin of bovine origin in modified Ringer’s lactate solution.

Description

Chemical name

  • Hemoglobin glutamer.

Physical properties

  • Sterile dark-purple solution.
  • Osmolality: 300 mOsm/kg.

Storage requirements

  • Store at room temperature or refrigerated (up to 3 years).
  • Do not freeze.
  • Once the container is opened, Oxyglobin® should be used within 24 h.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Anemia (regardless of the cause).
  • Useful when a blood transfusion is not available.
  • Oxyglobin® is up to 10x more effective than blood when given during fluid resuscitation to animals in hemorrhagic shock.
  • Expensive.
    .

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

  • Text here

with diagnostic tests

  • ALT, AST, and total proteins may be increased.
  • May cause false increases of AST and creatinine.
  • May interfere with the determination of GGT, albumin or bilirubin.
  • Hemoglobinuria may be seen.
  • Oxyglobin will dilute blood and values for PCV and RBCC will not be accurate.
  • Urine dipstick measurements are inaccurate while gross discoloration of the urine is present

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed. Small Animal Formulary. Part B: Exotic Pets.  9th edn. BSAVA, UK.
  • Plumb D (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

Want more related items, why not
contact us

MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code