ISSN 2398-2985      

Flutamide

4ferrets

Synonym(s): Eulexin


Introduction

Name

  • Flutamide.

Class of drug

  • Androgen inhibitor.

Description

Chemical name

  • 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide.

Molecular formula

  • C11H11F3N2O3.

Molecular weight

  • 276.21.

Physical properties

  • Buff to yellow powder.

Storage requirements

  • Store at controlled room temperature (20-25°C/68-77°F).

Uses

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Indications

  • Reports of its use in ferrets are anecdotal.
  • It is used to treat prostatic disease secondary to adrenal tumors.
  • Further investigation of this drug in ferrets is recommended as it has been associated with increases in testicular and mammary tumors in rats.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Flutamide enhances the effects of warfarin.

Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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