ISSN 2398-2985      

Epoetin alpha

4ferrets

Synonym(s): Epoetin alfa, Epogen, EPO


Introduction

Name

  • Epoetin alpha.

Class of drug

  • Erithropoietic agent.
  • Human erythropoietin produced in cell culture using recombinant DNA technology.

Description

Chemical name

  • Text here

Molecular formula

  • C815H1317N233O241S5.

Molecular weight

  • 18396.1.

Physical properties

  • Commercially available as a sterile, preservative-free, colorless solution.

Storage requirements

  • The injectable solution should be stored in the refrigerator.
  • Do not freeze.
  • Do not shake.
  • Protect from light.
  • Use each vial as a single use.​
  • This drug is abusable, particularly by people practising some sports. It should therefore be stored accordingly.

Uses

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Indications

  • Anemia resulting from chronic kidney failure, hyperestrogenism or pure red cell aplasia (immune mediated).
  • Due to expense and potential risks associated with its use, it is reserved for patients with a PCV lower than 15-20%.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Probenecid reduces renal tubular excretion of EPO.
  • Desmopressin can decrease bleeding times when combined with EPO. ​

Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Malka S, Hawkins M, Zabolotzky S et al (2010) Immune-mediated pure red cell aplasia in a domestic ferret. JAVMA 237 (6), 695-700 PubMed.
Other sources of information
  • Johnson-Delaney C A (2017) Ferret Medicine and Surgery. CRC Press, USA. pp 514.
  • Meredith A (2015) Ed Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, Quedgeley, UK. pp 338.
  • Plumb D C (2008) Plumb's Veterinary Drug Handbook. 6th edn. Blackwell Publishing, USA. pp 1120.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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