ISSN 2398-2985      

Bupivacaine

4ferrets

Introduction

Name

  • Bupivacaine.

Class of drug

  • Local anesthetic.

Description

Chemical name

  • 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide.

Molecular formula

  • C18H28N2O.

Molecular weight

  • 288.43.

Physical properties

  • Clear, sterile solution.
  • Soluble in ethanol and water.
  • Slightly soluble in acetone and chloroform.

Storage requirements

  • Store at controlled room temperature and protected from light.

Uses

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Indications

  • Used predominantly as a local anesthetic.
  • Has a longer duration of action than most other local anesthetic agents.
  • Effects not seen for up to 30 min but usually within 15-20 min.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

Propranolol
  • May increase bupivacaine effects if administered concurrently.
Other local anesthetics
  • Dose of bupivacaine should be reduced when used in combination with other local anesthetics.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lichtenberger M & Ko J (2007) Anaesthesia and Analgesia for Small Mammals and Birds. Vet Clin North Am Exotic Anim Pract 10 (2), 293-315 PubMed.

Other sources of information

  • Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
  • Ramsey I et al (2011) Bupivacaine. In: BSAVA Small Animal Formulary. 7th edn. BSAVA.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
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