Exotis ISSN 2398-2985

Ferrets

Pyogranulomatous panophthalmitis

Contributor(s): Cathy Johnson-Delaney, David Perpinan

Introduction

  • Panophthalmitis with pyogranulomatous lesions.
  • Cause: ferret systemic coronavirus (FRSCV).
  • Signs: corneal opacity, poor body condition, lethargy, dehydration, azotemia.
  • Diagnosis: immunohistochemistry, necropsy, radiography, ultrasonography.
  • Treatment: none; supportive.
  • Prognosis: poor.

Pathogenesis

Etiology

  • One reported case of systemic coronavirus with associated unilateral ocular disease.

Pathophysiology

  • Similar to cats with feline infectious peritonitis.

Timecourse

  • Clinical signs appear weeks to months after infection.
  • When clinical signs are detected, natural death or euthanasia usually occurs within 2 months.

Epidemiology

  • The disease may initially present in a geographical area as an outbreak, followed by years with low incidence.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Lindemann D M, Eshar D, Schumacher L L et al (2016) Pyogranulomatous panophthalmitis with systemic coronavirus disease in a domestic ferret (Mustela putorius furo). Vet Ophthal 19 (2), 167-171 PubMed.
  • Perpiñán D & López C (2008) Clinical aspects of systemic granulomatous inflammatory syndrome in ferrets (Mustela putorius furo). Vet Rec 162 (6), 180-184 PubMed.

Other sources of information

  • Kiupel M & Perpiñán D (2014) Viral Diseases of Ferrets. In: Biology and Diseases of the Ferret. 3rd edn. Eds: Fox J G & Marini R P. Wiley Blackwell, USA. pp 439-517.


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