Exotis ISSN 2398-2985


Ovarian neoplasia

Contributor(s): Cathy Johnson-Delaney, Vicki Baldrey


  • Cause: neoplastic and pre-neoplastic changes in the ovaries.
  • Signs: usually none.
  • Diagnosis: abdominal palpation, ultrasonography.
  • Treatment: ovariohysterectomy.
  • Prognosis: good.



  • In jills, smooth muscle hyperplasia was found in a large number of ovaries in a published report.
  • Leiomyomas found in a significant number of ovaries, sometimes unilaterally or bilaterally.
  • They may be solitary or multiple, reaching a diameter of 1.8 cm; most are smaller.
  • Visible macroscopically as an opaque white solid mass against the pinkish-gray ovarian tissue; well defined and show ovarian tissue stretched over their surface.
  • Occasionally the myoma is embedded in the ovary.
  • The intra-ovarian myomatous tissue may be continuous with the hyperplastic smooth-muscle tissue.
  • Hydrometra (aseptic fluid within the uterus) and a persistent corpora lutea are seen.
  • Other reported ovarian neoplasms include teratoma, Leydig cell tumor and granulosa cell tumor.


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Further Reading


Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Patterson M M, Rogers A B, Schrenzel M D, Marini R P & Fox J G (2003) Alopecia attributed to neoplastic ovarian tissue in two ferrets. Comp Med 53 (2), 213-217.
  • Rodriguez J L et al (1994) Ovarian teratoma in a ferret (Mustela putorius furo): a morphological and immunohistochemical study. J Zoo Wildl Med 25 (2), 294-299.
  • Cotchin E (1980) Smooth-muscle hyperplasia and neoplasia in the ovaries of domestic ferrets (Mustela putorius furo). J Pathol 130 (3), 169-171.

Other sources of information

  • Pollock C G (2012) Ferrets: Disorders of the Urinary and Reproductive Systems. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier Saunders, St Louis. pp 46-61.
  • Fisher P G (2009) Ferrets: Urogenital and Reproductive System Disorders. In: Manual of Rodents and Ferrets. Eds: Keeble K & Meredith A. BSAVA, Gloucester. pp 291-302.