Exotis ISSN 2398-2985

Ferrets

Nephrosis/nephritis

Contributor(s): Cathy Johnson-Delaney, Vicki Baldrey

Introduction

  • Cause: degenerative changes due to age.
  • Signs: non-specific illness.
  • Diagnosis: radiography, ultrasonography, urinalysis, hematology, blood chemistries, FNA or biopsy, urine culture and sensitivity, urine cytology.
  • Treatment: antimicrobials, fluid therapy, supportive care.

Pathogenesis

Etiology

  • Changes within the kidney; ascending infection or secondary infection from a systemic infection may affect the kidney.
  • Nephrosis generally is a degenerative disease seen in geriatric ferrets and may be found incidentally at necropsy.
  • Ferrets can have an inflammatory, immune-mediated/infected nephritis but this may only be picked up on necropsy as no outward signs may be seen.
  • It may lead to end stage kidney disease with elevated BUN and creatinine, electrolyte imbalance.
  • Immune mediated/complex disease may eventually result in renal failure Renal failure.

Diagnosis

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Treatment

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Further Reading

Publications

Refereed papers

Other sources of information

  • Pollock C G (2012) Ferrets: Disorders of the Urinary and Reproductive systems. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier Saunders, St Louis. pp 46-61.
  • Fisher P G (2009) Ferrets: Urogenital and Reproductive System Disorders. In: Manual of Rodents and Ferrets. Eds: Keeble K & Meredith A. BSAVA, Gloucester. pp 291-302.


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