Exotis ISSN 2398-2985

Ferrets

Myasthenia gravis

Synonym(s): MG

Contributor(s): Cathy Johnson-Delaney, David Perpinan

Introduction

  • An autoimmune disease of the muscles, including the esophagus.
  • Cause: antiacetylcholine receptor antibodies.
  • Signs: hindlimb weakness, flaccid paraparesis -> tetraparesis, megaesophagus, vomiting, weight loss.
  • Diagnosis: nerve conduction velocity testing, serology, muscle biopsy/histopathology, radiography.
  • Treatment: pyridostigmine bromide, prednisolone; administration of critical care formula; famotidine.

Pathogenesis

Etiology

  • Due to antiacetylcholine receptor antibodies.

Diagnosis

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Treatment

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Couturer J, Huynh M, Boussarie D, Cauzinille L & Shelton G D (2009) Autoimmune myasthenia gravis in a ferret. J Am Vet Med Assoc 235 (12), 1462-1466 VetMedResource.


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