Exotis ISSN 2398-2985

Ferrets

Histoplasmosis

Synonym(s): Histoplasma capsulatum infection

Contributor(s): Cathy Johnson-Delaney, David Perpinan

Introduction

  • This disease has recently been described.
  • Cause: infection with Histoplasma capsulatum.
  • Signs: green/mucoid diarrhea, thrombocytopenia, hypocalcemia, bilirubinuria.
  • Diagnosis: exploratory laparotomy, liver biopsy, laboratory testing, radiography.
  • Treatment: itraconazole/amphotericin B nebulization, euthanasia.
  • Prognosis: [text]

Pathogenesis

Etiology

  • Infection with Histoplasma capsulatum; a fungal disease that tends to grow in avian nitrogen rich feces.

Predisposing factors

General

  • Outdoor ferrets, hunting ferrets and other ferrets exposed to soil and bird feces.

Pathophysiology

  • Infection probably by inhalation.
  • The disease can have just pulmonary involvement or disseminate to other organs.
  • Disseminated disease can produce a variety of clinical signs.

Epidemiology

  • Rare occurrence in ferrets.

Diagnosis

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Treatment

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Prevention

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Further Reading

Publications

Refereed papers

Other sources of information

  • Greenacre C B, Dowling M & Nobrega-Lee M (2015) Histoplasmosis in a group of domestic ferrets (Mustela putorius furo). In: Proc Exotics Con. San Antonio, TX, USA. Session 169. pp 363.
  • Fox J G & Marini R P (2014) Biology and Diseases of the Ferret. 3rd edn. Wiley Blackwell, USA. pp 835.
  • Greene C E (2006) Infectious Diseases of the Dog and Cat. 3rd edn. Saunders Elsevier, USA. pp 1387.


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