Exotis ISSN 2398-2985

Ferrets

Eosinophilic gastroenteritis

Synonym(s): Eosinophilic granulomatous disease, EG, EGE

Contributor(s): Cathy Johnson-Delaney, Sarah Pellett

Introduction

  • The condition is also referred to as eosinophilic granulomatous disease, as it may affect other organs, including mesenteric lymph nodes and, less frequently, liver and lungs.
  • Rare in ferrets.
  • Cause: unknown. Accumulation of eosinophils in the gastrointestinal mucosa.
  • Signs: diarrhea, weight loss, anorexia, lethargy dehydration, vomiting.
  • Diagnosis: hematology/serum chemistries, abdominal palpation, laparotomy, serology.
  • Treatment: corticosteroids, prednisolone, critical care nutrition, surgery, ivermectin.
  • Prognosis: guarded to poor.

Pathogenesis

Etiology

  • Etiology is unknown.

Pathophysiology

  • Substances within the granules in eosinophils, directly damage the surrounding tissues causing inflammation and thickening.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lennox A M (2005) Gastrointestinal diseases of the ferret. Vet Clin North Am Exotic Anim Pract 8 (2), 213-225 PubMed.

Other sources of information

  • Perpiñán D & Johnson-Delaney C A (2017) Disorders of the Digestive System and Liver. In: Ferret Medicine and Surgery. CRC Press, USA. pp 159-190.
  • Hoefer H L, Fox J G & Bell J A (2012) Gastrointestinal Diseases. In: Ferrets, Rabbits and Rodents. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier, St. Louis, USA. pp 27-45.
  • Burgess M E (2007) Ferret Gastrointestinal and Hepatic Diseases. In: Ferret Husbandry, Medicine and Surgery. 2nd edn. Ed: Lewington J H. Saunders, Philadelphia, USA. pp 203-223.


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