Equis ISSN 2398-2977

Uterus: clearance - scintigraphy

Synonym(s): Uterine clearance scintigraphy

Contributor(s): Russel Malton, Rachel Murray

Introduction

  • Impaired uterine clearance during estrus is considered to be a major cause of recurrent endometritis. Some older multiparous mares have a dysfunctional mechanical clearance of inflammatory products during estrus making them susceptible to recurrent endometritis. 
  • Scintigraphy can be used to evaluate mechanical clearance of the uterus and offers a simple, minimally-invasive and potentially reliable means of diagnosing a delay in uterine clearance during estrus.
  • Studies have indicated that normal mares clear >50% of radiocolloid infused into the uterus within 2 h, whereas those susceptible to endometritis or mares with poor cervical dilatation show significantly reduced clearance.

Radiopharmaceutical

  • 99mTc-albumin colloid  (99mTc-AA): this radiocolloid has been chosen because of its ease of preparation and its higher target to background ratio compared with other radiocolloids.

Dosage

  • 370 GBq 99mTc-AA: no statistically significant difference in uterine clearance was noted with larger doses and image quality was similar.  The radiocolloid is buffered to pH 7 in a total volume of  2 ml or less.

Uses

  • Identification of delayed uterine clearance as a component of recurrent endometritis and consequent infertility or subfertility.

Requirements

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Preparation

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Procedure

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Aftercare

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Neuwirth L, LeBlanc M M, Mauragis D et al (1995) Scintigraphic measurement of uterine clearance in mares. Vet Radiol 36 (1), 64-68 VetMedResource.
  • LeBlanc M M, Neuwirth L, Asbury A C et al (1994) Scintigraphic measurement of uterine clearance in normal mares and mares with recurrent endometritis. Equine Vet J 26 (2), 109-113 PubMed.


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