ISSN 2398-2977      

Lung: biopsy

pequis
Contributor(s):

Nicola Menzies-Gow


Introduction

  • Histological and microbiological examination of lung biopsy material is useful in the diagnosis of certain lower respiratory tract diseases.

Uses

  • Investigation of lung disease in which lesions are localized and visible on ultrasonography or generalized.
  • Part of full diagnostic evaluation of respiratory tract Respiratory: physical examination.

Focal disease will require ultrasound guidance.

Advantages

  • Allows evaluation of pathological changes in lung disease.

Disadvantages

  • Some variation between degree of pathology on biopsy and clinical signs probably due to distribution of lesions and limited samples that can be taken.
  • A number of serious complications can occur.
  • Focal lesions require ultrasound guidance for representative sampling.
  • Should not be performed in animals in respiratory distress, with bleeding disorders, bullous or cavitating lesions, pulmonary hypertension or poor cardiorespiratory reserve.

Requirements

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Preparation

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Procedure

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Aftercare

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Outcomes

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Prognosis

  • Depends on underlying problem.

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Pusterla N, Watson J L, Madigan J E & Wilson W D (2007) Technique an diagnostic value of percutaneous lung biopsy and 66 horses with diffuse pulmonary diseases using an automated biopsy device. Equine Vet J 19 (3), 157-161 VetMedResource.
  • Raphel C F & Gunson D E (1981) Percutaneous lung biopsy in the horse. Cornell Vet 71 (4), 439-448 PubMed.

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