Equis ISSN 2398-2977

Blood typing

Contributor(s): Annalisa Barrelet, Han van der Kolk

Introduction

  • Cell surfaces are covered with molecules of various types and functions. Their presence is genetically determined. A lot of these molecules are specific for an individual within a species and are recognized by the immune system. They are calledallo-antigens.
  • The surfaces of red and white blood cells contain many of such allo-antigens.
  • Blood groups are based on the red blood cell allo-antigens.
  • There are seven different systems or loci associated with red blood cell typing in horses (A, C, D, K, P, Q and U). In addition, these seven systems include 34 different factors.
  • Anglo-arab   Anglo-Arab  horses might possess a special D system.

Uses

  • The major application of blood typing in horses is in the verification of parentage.
  • If one suspects neonatal isoerythrolysis   Immunology: neonatal isoerythrolysis  , the optimal time for testing the mare is during the last 3 weeks of gestation. Samples should be taken at 3-4 weeks and again at 1 week prior to full term.

Disadvantages

  • The availability of good standardized re-agents in sufficient quantity.

Requirements

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Preparation

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Aftercare

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Bowling AT, Eggleston-Stott M L, Byrns G, Clark R S, Dileanis S & Wictum E (1997) Validation of microsatellite markers for routine horse parentage testing. Anim Genetics 28, 247-252 PubMed.
  • Breen M, Lindgren G, Binns M M, Norman J, Irvin Z, Bell K, Sandberg K & Ellegren H (1997) Genetical and physical assignments of equine microsatellites - first integration of anchored markers in horse genome mapping. Mammal Genome 8, 267-273 PubMed.
  • Binns M M, Holmes N G, Holliman A & Scott A M (1995) The identification of polymorphic microsatellite loci in the horse and their use in thoroughbred parentage testing. Brit Vet J 151, 9-15 PubMed.
  • Kakoi H, Gawahara H & Miura N (1995) Unusual D system inheritance in Anglo-Arab horse. Anim Genetics 26 (1), 53-54 PubMed.
  • Becht J L & Semrad S D (1985) Hematology, blood typing, and immunology of the neonatal foal. Vet Clin North Amer (1), 91-116 PubMed.


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