ISSN 2398-2977      

Cytology: fine needle aspirate

pequis

Synonym(s): FNA


Overview

  • Microscopic study of cells obtained from skin, lymph nodes, body fluids/exudates, masses or internal organs.
  • Cells are smeared onto a slide and stained, then viewed by light microscopy.
  • Rapid results.
  • Requires minimal equipment.
  • However, cells in exudates may be difficult to separate/concentrate and stain usefully.
  • Direct evaluation of neoplastic/inflammatory changes provided representative sample obtained.
  • Requires skilled cytopathologists as some apparently neoplastic changes can be "normal".

Sampling

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Tests

Methodologies

Availability

  • Readily available and easy to perform.
  • Minimally invasive and little distress to the patient.
  • Cheap and simple test.

Validity

Sensitivity

  • Less sensitive than histopathology because architectural detail is lacking and more difficult to obtain representative sample.
  • More difficult to assess cell types.
  • Requires cytopathologist.

Specificity

  • Low compared to histopathology as may miss abnormal cells.
  • Good for discrete cell tumors, eg lymphoma, mast cell, squamous cell carcinoma.

Technique (intrinsic) limitations

  • Information about tissue architecture cannot be obtained.
  • Often requires confirmation by histopathology.

Technician (extrinsic) limitations

  • May be difficult to obtain representative sample.
  • Skill required.
  • Fairly low repeatability.

Result Data

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Cowell R L & Tyler R D (1992) Cytology and Hematology of the Horse. Mosby, USA.

Related Images

MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code