Equis ISSN 2398-2977

CSF: cytology

Contributor(s): Frank Andrews, Kathleen P Freeman, Caroline Hahn

Overview

  • Changes most dramatically with inflammation, being more reliable in acute conditions.
  • The type and number of cells helps identify cause   CSF: cell count and differential  .

Sampling

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Tests

Methodologies

  • Total cell count with hemocytometer.
  • Giemsa-stained smear of fluid directly or of cells concentrated by centrifugation, sedimentation, membrane filtration.

Availability

  • Widely available.

Technique (intrinsic) limitations

  • CSF samples can be contaminated with blood, this necessitates correction of cell count and differential   CSF: cell count and differential  .
  • CSF cytology changes as CNS illness progresses.

Results Data

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Further Reading

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