Equis ISSN 2398-2977

CSF: creatine kinase

Synonym(s): Creatinine kinase, CK

Contributor(s): Frank Andrews, Annalisa Barrelet, Caroline Hahn

Overview

  • An isoenzyme specific to the brain: increases in the cerebrospinal fluid (CSF), along with some other enzymes, in central nervous system (CNS) disease.

Sampling

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Tests

Methodologies

  • Standard enzymatic method.

Validity

Sensitivity

  • The sensitivity of CSF [CK] is not sufficient for diagnosis of a specific disease.

Specificity

  • The specificity of CSF [CK] is not sufficient for diagnosis of a specific disease.

Result Data

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Further Reading

Publications

Refereed papers

  • Johnson P J & Constantinescu G M (2000)Collection of cerebrospinal fluid in horses. Equine Vet Educ12, 7-12.
  • Johnson P J & Constantinescu G M (2000)Analysis of cerebrospinal fluid in horses. Equine Vet Educ12, 13-17.
  • Furr M O & Tyler R D (1990)Cerebrospinal fluid creatine kinase activity in horses with central nervous system disease - 69 cases (1984-1989). JAVMA197(2), 245-248.

Other sources of information

  • Coles E H (1980)Veterinary Clinical Pathology.3rd edn. Philadelphia: WB Saunders Co. (Review on CSF enzymology).


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