ISSN 2398-2977      

Blood: biochemistry - magnesium

pequis

Synonym(s): Mg


Overview

  • Magnesium (Mg) is involved with calcium   Blood: biochemistry - calcium  and phosphorus   Blood: biochemistry - phosphate  metabolizm and is involved in numerous enzyme systems.
  • Approximately 80% of magnesium is diffusible with 35% of serum Mg bound to protein.
  • Fourth most prevalent cation in body (after Na, Ca and K) and is second most prevalent soft tissue cation (after K).
  • Plasma/serum Mg may represent <1% of total body magnesium.
  • Magnesium balance controlled by gastrointestinal tract absorption and renal excretion. May be excreted in the colon in the horse.
  • Important catalyst for multiple enzymes, including ATP.
  • Decreased magnesium can result in intracellular K loss and decreased total body K.
  • Ionized magnesium acts as ionized calcium antagonist.
  • Extracellular magnesium is important in production and decomposition of acetylcholine.
  • Hypomagnasemia may result in tetany due to accentuated ionized calcium action and increased acetylcholine release.

Sampling

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Tests

Methodologies

  • Ion-selective electrode (ionized magnesium).
  • Colorimetric assay.
  • Kinetic assay.
  • Atomic absorption spectrophotometry.

Availability

  • Not routinely offered in chemistry profiles. Usually must request separately.

Technique (intrinsic) limitations

  • Other laboratory and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

Other sources of information

  • Kaneko J J, Harvey J W & Bruss M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.

Organisation(s)

  • Veterinary commercial laboratories, State diagnostic laboratories or Veterinary College laboratories.

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