Equis ISSN 2398-2977

Blood: biochemistry - gamma globulins

Synonym(s): Ig, gamma globulin, immunoglobulin

Contributor(s): Annalisa Barrelet, Kathleen P Freeman, Frank Taylor

Overview

  • Fraction of total globulins.
  • Multiple classes exist, including IgG, IgM, IgA, IgE and IgD.

Sampling

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Tests

Methodologies

  • Turbidometric assay.
  • CITE test (idexx) - semiquantitative.
  • Zinc sulfate turbidity test.
  • Latex agglutination test.
  • Electrophoresis.
  • Radial immunodiffusion (RID) test - 'gold standard' - for specific immunoglobulin classes. Requires overnight incubation.

Availability

  • Widely available. Check with laboratory for method(s) available.

Technician (extrinsic) limitations

  • Electrophoresis: more sophisticated techniques or RID. May not have exact correspondence with immunoglobulinn levels measured by other techniques.

Result Data

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Further Reading

Publications

Other sources of information

  • Morris D D (1998)Disorders of the Immune System.In: Equine Internal Medicine.Eds: S M Reed & W M Bayly. Philadelphia: W B Saunders. pp 47-53.
  • Kaneko J J, Harvey J W & Bruss M L (1997) Eds Clinical Biochemistry of Domestic Animals.5th edn. Academic Press, Boston.

Organisation(s)

  • Veterinary commercial laboratories, State diagnostic laboratories or Veterinary College laboratories.


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