Equis ISSN 2398-2977

Blood: biochemistry - creatinine

Synonym(s): Serum creatinine

Contributor(s): Annalisa Barrelet, Kathleen P Freeman, Frank Taylor

Overview

  • Derived from breakdown of creatine in muscle.
  • Excreted by kidneys.
  • Not influenced by protein metabolism (unlike urea).
  • Important marker of renal function; levels controlled by excretion rate: daily production and excretion remarkably constant rate related to body mass.

Sampling

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Tests

Methodologies

  • Colorimetric method.
  • Creatinine in alkaline solution reacts with picrate to form a colored complex. The rate of formation of the complex is measured.

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Interpret in conjunction with other laboratory and clinical findings.

Result Data

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Further Reading

Publications

Other sources of information

  • Kaneko J J, Harvey J W & Bruss M L (1997) EdsClinical Biochemistry of Domestic Animals. 5th edn. Academic Press, Boston.

Organisation(s)

  • Veterinary commercial laboratories, State diagnostic laboratories or Veterinary College laboratories.


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